Medicines can help you live better with chronic pain. You may use over-the-counter or prescription medicines. It can take some time, and trial and error, to work out the best treatment plan . Work with your healthcare provider to find the best medicines for you. And learn to use your medicine safely so that they work well.
A part of your treatment plan
Depending on the type of pain you have, you may take medicines:
At times when pain is worse than usual
For pain relief throughout the day
Before activities that tend to trigger pain. These might be when going shopping or doing physical therapy.
To lower sensitivity to pain and help you sleep
Four major groups of medicines are used to treat chronic pain. Each is described below.
These include the commonly used medicine acetaminophen. They also include non-steroidal anti-inflammatory medicines (NSAIDs) such as aspirin, ibuprofen, naproxen sodium, and ketoprofen. These all help control pain, but NSAIDs also help ease swelling (inflammation). These medicines are available over the counter. Some NSAIDS are available by prescription only.
Acetaminophen can cause liver damage if you take more than the recommended dose. NSAIDs may cause stomach problems such as bleeding ulcers. Using them over a long time can cause heart problems and stroke in a very small number of people. These medicines aren't addictive.
This includes medicines such as morphine, oxycodone, codeine, fentanyl, and methadone. Opioids may be used to treat more severe types of pain. Opioids are available only by prescription. These medicines may also work to manage chronic pain, but they may be abused. They also have unpleasant and possibly dangerous side effects.
This group includes medicines that were originally made to treat other conditions but were also found to ease pain. Examples of adjuvant medicines are antidepressants and anticonvulsants.
These help pain by working on the same brain chemicals that play a role in depression. They also help improve sleep. Tricyclic antidepressants are one group of antidepressants used to treat chronic pain caused by nerve injury (neuropathic pain). Examples include amitriptyline, nortriptyline, and desipramine. Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine and milnacipran are also used.
Some types of antidepressants are used in low doses for sleep problems. They may also be prescribed if you are very sensitive to pain or have certain kinds of nerve pain.
Anticonvulsants were developed to prevent seizures. These medicines can help certain pain conditions, particularly nerve (neuropathic) pain. Examples include gabapentin and pregabalin.